Welcome to SMILE, Karolinska University Hospital,
Huddinge
SMILE, Stockholm Medical Imaging Laboratory and Education, was founded in 2001
with the purpose of facilitating image analysis and evaluation
of digital data from research within MRI, SPECT and PET. SMILE
became a core facility at Karolinska University Hospital in 2004 and
functions as a hub where PhD students and researchers
can meet and take advantage of the collected competence in various image analysis methods
and utilize the powerful computers installed at the laboratory.
All projects are welcome, as long as they are associated with
Karolinska University Hospital or Karolinska Institute.
The cost of using the SMILE resources is regulated by the control group, and depends on the level of usage.
Please ask the manager for an up-to-date price list.
The Imagelab has hardware consisting of high speed
computers and large storage capabilities. On the software side
various advanced analysis programs are available, such as
Brainvoyager for fMRI evaluations, the mathematical tool Statistica,
and FSL
and Hermes for volumetric measurements (see further under
Software).
A network which connects all of Huddinge Hospital with SMILE
has been developed, and images can be transferred and stored
for research purposes from all clinical imaging modalities.
Temporary research space is also available at SMILE, as well
as a small library with scientific literature and journals.
PhD students can perform part of their scientific work at the
laboratory, such as image analysis and statistical computing,
and in addition meet tutors and fellow students for fruitful
seminars and scientific discussions. At SMILE supervision on
how to use the different image analysis tools and computer
systems can be received, and it is possible to perform basic
programming in order to modify and adapt the software. The
laboratory is managed by Eva Örndahl.
Examples of present and past activities are given under the
tab Research.
To date, SMILE has among other projects assisted with evaluations
of structural MRI studies, SPECT studies on large populations
and evaluations of fMRI experiments, and a number of theses have been published
with substantial aid from SMILE.
You may also download our brochure describing the resources
available at SMILE.
Note: the homepage is at the moment undergoing revision and
updating, which may lead to non-functioning pages and links.
We apologize for the inconvenience and are working to create
the new site as soon as possible.
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Spring at the Karolinska University Hospital, Huddinge.
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Grey Matter and Cognitive Patterns in Cognitive Impaired Subjects Using CSF Biomarker Cut-Offs
Miralbell J, Spulber G, Hooshmand B, Besga A, Mataró M, Cedazo-Minguez A, Kivipelto M, Wahlund LO.
J Alzheimers Dis. 2012 Feb 13. [Epub ahead of print]
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Structural brain changes and cognition in relation to markers of vascular dysfunction.
Miralbell J, Soriano JJ, Spulber G, López-Cancio E, Arenillas JF, Bargalló N, Galán A, Barrios MT, Cáceres C, Alzamora MT, Pera G, Kivipelto M, Wahlund LO, Dávalos A, Mataró M.
Neurobiol Aging. 2011 Oct 18. [Epub ahead of print]
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Shape analysis of the neostriatum in subtypes of frontotemporal lobar degeneration: Neuroanatomically significant regional morphologic change.
Looi JC, Walterfang M, Styner M, Niethammer M, Svensson LA, Lindberg O, Ostberg P, Botes L, Orndahl E, Chua P, Velakoulis D, Wahlund LO.
Psychiatry Res. 2011 Feb 28;191(2):98-111.
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[more publications]
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